The use of Duratia 60 Mg
Premature ejaculation (PE) is one of the most common sexual complaints.
It affects more than 20 to 40% of men who get early ejaculation than the desired time.
As men reach orgasm in barely two minutes, the long-lasting partners on bed become unsatisfied and hamper the interpersonal relationships.
Duratia 60 Mg— rich in Dapoxetine compound helps in maturing the ejaculation time.
It’s a medical panacea for delaying the ejaculation and furnishing a healthy relationship.
How does it work
Let’s check how a non-PE body differs with the PE body.
- Non-PE body
A healthy non-PE body needs sufficient amount of sexual stimulation for erection and ejaculation.
When the person is stimulated, the blood flows into the penis making a firm erection.
The persistent erection and decent testosterone level mix the sperm with the seminal fluid.
The mixture ultimately produces semen.
The semen is released when the man reaches his stimulation threshold.
- PE body
Performance anxiety and depression cause PE in most of the men
The lower level of serotonin chemical in the brain compels men to ejaculate early.
Serotonin transporter (SERT) is known to terminate the action of Serotonin— a neurotransmitter chemical which causes happiness and inculcates the feeling of well-being.
As a result, the low level of serotonin causes anxiety and hurried sex leading to early semen discharge.
Men with erectile dysfunction also develop PE. As they fear the loss of erection, they form a habit of rushing to the orgasm.
- PE-body with Duratia 60 Mg
When you administer Dapoxetine (originally built as an antidepressant) in the body, you are inhibiting the Serotonin Transporter.
Dapoxetine blocks the action of Serotonin transporter as it’s a famous serotonin reuptake inhibitor (SRI).
As the activity of Serotonin is elevated in the nervous system, the ejaculation is delayed.
The drug increases the intravaginal ejaculation latency time (IELT)— the time taken to eject during vaginal penetration.
Studies have proved that Duratia 60 Mg has a durative impact on the adversaries of the premature ejaculation than the depression.
The direction for usage
- Before you advance for taking any PE medicine, ensure that you’ve got the prescribed dose from the doctor and you’ve read the leaflet information.
- It’s an oral medication which should be used 1 to 3 hours before the sexual episode.
- Under the correct administration, the drug potentiates its positive impact for more than 4 hours.
- It should be swallowed with the water.
- The food intake doesn’t affect the extent and the rate of absorption of the drug. Hence, you can take it with or without the food.
- Induce the drug in its original state— oral route for oral medication.
The route of admission
We strictly bind users to take the medicines for the manners they are made.
As Duratia 60 Mg is in the tablet form, admit the drug in the body orally.
Avoid breaking or mashing the pill into the granular solution for higher bioavailability in the circulatory system through the intravenous route.
Pills are designed as per the bioavailability and any change in it could over or under dope your body causing undesirable side-effects.
Pharmacokinetics of Duratia 60 Mg
- The pharmacokinetics of Duratia 60 Mg, i.e., the distribution of the drug in the body is nearly unaffected by the current state of mood, food intake, etc.
- However, studies suggest that fat ingestion in the body has a very modest effect on the effectivity of the drug.
- Also, the age of the person has very little to do in delaying the action of Duratia 60 Mg.
- Beverages like Alcohol, Coffee, etc. may increase the probability of the side-effects but does not influence the drug operation.
What’s your ideal dose?
Doctors have to carry a few hit and trials to decide your dose.
They usually check your medical condition, previous dosage, and their forms, and assess everything responsible in determining your PE regimen.
Hence, we encourage you to state every minute detail explicitly without any hesitation.
Here’s what the doctors might ask you and how your transparent responses could get you the right dose:
- Have you used Duratia 60 Mg before?
If you have never used Duratia 60 Mg— you fall in the beginners' category. The doctor prescribes the minimum dose level, i.e., Duratia 60 Mg 30 mg for the beginners who were never associated with Duratia 60 Mg. If you’ve been already utilizing it, you might have to give tolerance details for elevating or lowering the dose level.
- Can you tolerate the power of the medicine?
Doctors ask this for learning how the medicine behaves in the circulatory system and whether your body has tolerance power. If your body can’t bear the side-effects of the dosage volume, you will need to lessen the dose concentration, and if you fail to observe any impact on PE, you need to inflate the dose concentration to the next maximum recommended dose— 60 mg commonly.
- What other medicines do you take?
To get the breadth view of your medical condition and current medications, state everything in detail. Depending on the cross-reactions and contraindications, your doctor would determine the dose volume.
- What’s your sexual frequency?
If you have multiple-sexual episodes in a day, your doctor would strictly prohibit you from administering it multiple times on the same day. It’s a drug which should be taken when you anticipate sex but just once in 24 hours. There are other daily medicinal dosage.
When to seek a doctor?
- When Duratia 60 Mg has no worthy effect on the premature ejaculation
- When Duratia 60 Mg imparts unwanted but inevitable corollary consequences
- When you intake Duratia 60 Mg more than the prescribed volume
Side effects of Duratia 60 Mg
Duratia 60 Mg seems to project its side-threats in the initial month of the prescription.
It launches common to rare side-effects varying from person-to-person tolerability.
Here are some of the extremely common side-effects:
Here are some of the Common side effects:
- insomnia and unusual dreams
- erection problems
- numbness and “pins and needles.”
- digestion problems like constipation, diarrhea or indigestion
- feeling and being sick
- sweating and flushing
- Nasal congestion
- concentration problems
- stomach pain or bloating
- tiredness and feeling sleepy
- shaking and trembling
- vision problems such as blurring
- a rise in blood pressure
- low libido
- dry mouth
- ringing in the ears
Here are some of the Uncommon side effects:
- dizziness when standing up or a spinning sensation
- changes in heart rate
- difficulty reaching orgasm
- weakness, fatigue, and drowsiness
- Changes in mood such as feelings of nervousness, excitement, apathy, paranoia or depression.
- feeling hot or abnormal
- vision problems, eye pain, dilated pupils
- cold sweat
- rise or drop in blood pressure
- grinding teeth
- Change in taste bud
Here are some of the rare side-impacts (1 in 10,000 people)
- The urgent need to clear the bowel
- Dizziness even after slight exertion
- suddenly falling asleep
Duratia 60 Mg Contraindications
The active component of Duratia 60 Mg may cross-react with the pharmaceutical ingredients of the other drugs ushering body towards the danger.
Few drugs are the strong reasons why it makes sense to withhold Duratia 60 Mg treatment.
Duratia 60 Mg should be avoided with these contraindicated drugs.
- Monoamine oxidase inhibitors
Monoamine oxidase inhibitors are the kind of antidepressant drugs which minimize or degrade the volume of monoamines— one of the critical factors for causing depression. The medications like Isocarboxazid (Marplan), Phenelzine (Nardil), Selegiline (Emsam), etc. should be strictly avoided with the Duratia 60 Mg.
It’s a drug used for treating psychological disorders like Schizophrenia and psychosis. The simultaneous use of Dapoxetine inhibits the metabolism of Thioridazine prolonging the effect of the drug causing dizziness and fainting.
Antibiotics like Linezolid halt the bacterial infection in the body. When antibiotics are used with Duratia 60 Mg, there could be a soaring level of Serotonin in the body. The excessive Serotonin neurotransmitter may alter the blood pressure rate, body temperature, life-threatening conditions like Serotonin Syndrome.
- Serotonergic analgesics
Certain painkillers like Tramadol are a good Serotonergic Agents. When Dapoxetine interacts with it, it may lead to severe threats like fever, tremors, muscle twitching, shivering, stiffness, etc.
- Serotonin making amino acids
Amino acids such as Tryptophan balance the nitrogen and create serotonin neurotransmitters. Avoid Duratia 60 Mg with such amino acids because you are already supplying enough serotonin creators in the body. Adding the drug to your lifestyle would increase the serotonin level.
- Other PE drug
You should shy away from Duratia 60 Mg if you’ve been already in letting other PE drugs.
What if you miss the daily dose
Duratia 60 Mg is not designed for the daily purpose. As the onset of the drug stays for 4-5 hours, limit your dose to once in 24 hours.
The advantage of Duratia 60 Mg is— you don’t have to take it daily necessarily. Use it during the sexual anticipation.
What should you do in the case of overdose
Duratia 60 Mg is well-tolerated in the clinical research. It has a flexible-dose regimen.
However, the reported side-effects of the overdose are mild or moderate.
Halt the dose and rush to the doctor if the moderate morbid conditions trouble you.
Do’s and Don’ts
- The bioavailability of Duratia 60 Mg is 42%. Don’t use the intravenous path of admission for a higher rate of absorption.
- Take the pill in its original and complete form.
- Don’t break or chew the pill.
- It’s not made for women.
- It’s not developed for kids below 16 years and pets.
- Stick to the prescribed route of administration.
- Skim through the patient information leaflet for further details.
- Don’t assist ideas or hand over the pills to the people who share the same symptoms. Instead, brief them about the essential role of the doctors in treating PE.
- Don’t self-medicate yourself or get influenced by others opinion. Take counsel from the certified doctors and follow up the medical instruction.
- Plan your Duratia 60 Mg intake based on the current medication.
- Dispose of the expired medicine away from other’s reach.
- Stay away from the counterfeited tablets.
Where should you store Duratia 60 Mg
- Duratia 60 Mg doesn’t need special storage, however; keeping it away from the direct sunlight will prevent the modest degradation of the drug.
- Also, it should be beyond the reach of kids and pets.
Fortune Healthcare is a licensed Duratia 60 Mg maker— complying with all the rules of the FDA and the local governments.
High clinical testing under the supervision of medical experts ascribes to the success of the product.
Fortune Healthcare has made sure that:
The active substance remains dapoxetine.
The inactive substances continue to have two parts.
Tablet core: croscarmellose sodium, magnesium stearate, lactose monohydrate, colloidal anhydrous silica, microcrystalline cellulose.
Tablet layer: hypromellose, Iron Oxide Yellow (E172), titanium dioxide (E171), lactose monohydrate, Iron Oxide Black (E172), triacetin
Each drug is bioequivalent to each other and has the same intent and purpose by all mean.
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